A supernatural medical drama that centers around the lives of the doctors and nurses of Hope Zion Hospital.

The story of sisters Lillian and Grace who open an orphanage in the 1916 Western town of Brookfield. Caught between the traditions of cattle ranchers and the ambitions of a growing town, they strive to find romance and happiness while overcoming the challenges of helping the children in their care.

Geneticist David Sandstrom is the chief scientist at the prestigious virology/micro-biology NORBAC laboratory, a joint enterprise between the USA, Canada and Mexico for countering bio-terrorism.

A young woman's murder causes the subjects of a century-long mission to populate a new world to question the true nature of the project as they approach the point of no return.

A gifted heart surgeon excels in her new leadership role as Chief of Surgery after her renowned boss falls into a coma. When her former boss wakes up months later demanding to resume his duties, Sam is tasked with supervising this egotistical expert with a scalpel who never acknowledged her stellar talent.